概述

  • 产品名称Anti-MCPIP1抗体
    参阅全部 MCPIP1 一抗
  • 描述
    兔多克隆抗体to MCPIP1
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to a sequence within amino acids 291-474 of Human MCPIP1 (NP_079355).

  • 阳性对照
    • 293T, A431, H1299, HeLa, HepG2 and Raji whole cell lysates; HeLa cells; CA922 Xenograft.

性能

应用

Our Abpromise guarantee covers the use of ab97910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.
  • 序列相似性Belongs to the ZC3H12 family.
    Contains 1 C3H1-type zinc finger.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • dJ423B22.1 antibody
    • MCP 1 treatment-induced protein antibody
    • MCP-induced protein 1 antibody
    • MCP1-induced protein antibody
    • MCPIP 1 antibody
    • MCPIP antibody
    • Ribonuclease ZC3H12A antibody
    • RP3-423B22.1 antibody
    • ZC12A_HUMAN antibody
    • ZC3H 12A antibody
    • ZC3H12 A antibody
    • Zc3h12a antibody
    • Zinc finger CCCH domain-containing protein 12A antibody
    • Zinc finger CCCH type containing 12A antibody
    see all

Anti-MCPIP1 antibody 图像

  • Anti-MCPIP1 antibody (ab97910) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 66 kDa
  • ab97910 at 1/200 dilution staining MCPIP1 in HeLa cells by Immunofluorescence, Paraformaldehyde fixed. Lower image shows cells co-stained with Hoechst 33342.
  • ab97910 at 1/100 dilution staining MCPIP1 in CA922 Xenograft by Immunohistochemistry, Paraffin-embedded tissue.

Anti-MCPIP1 antibody (ab97910)参考文献

ab97910 has not yet been referenced specifically in any publications.

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