概述

  • 产品名称
    Anti-MCP4抗体[500-M70]
    参阅全部 MCP4 一抗
  • 描述
    小鼠单克隆抗体[500-M70] to MCP4
  • 经测试应用
    适用于: ELISA, Neutralisingmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant hMCP-4 (human Macrophage/Monocyte chemotactic protein-4).

性能

  • 形式
    Lyophilised:Reconstitute with 500µl of sterile water.
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    PBS, pH 7.4, no preservative, sterile filtered
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    单克隆
  • 克隆编号
    500-M70
  • 骨髓瘤
    unknown
  • 同种型
    IgG1
  • 轻链类型
    unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab9559 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
Neutralising
  • 应用说明
    NEUTRALIZATION:To yield one-half maximal inhibition [ND50] of the biological activity of rMCP-4 (100ng/ml), a concentration of 1-5µg/ml of the antibody is required.

    ELISA:This antibody can be used at a concentration of 1-2µg/ml, as a capture antibody in conjunction with a compatible secondary reagent to yield satisfactory results in a sandwich ELISA (using 100µl/well antibody solution).
  • 靶标

    • 功能
      Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
    • 组织特异性
      Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
    • 序列相似性
      Belongs to the intercrine beta (chemokine CC) family.
    • 翻译后修饰
      One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C-C motif chemokine 13 antibody
      • CCL13 antibody
      • CCL13_HUMAN antibody
      • Chemokine (C C motif) ligand 13 antibody
      • CK beta 10 antibody
      • CK-beta-10 antibody
      • CKb10 antibody
      • MCP-4 antibody
      • MGC17134 antibody
      • Monocyte chemoattractant protein 4 antibody
      • Monocyte chemotactic protein 4 antibody
      • NCC 1 antibody
      • NCC-1 antibody
      • NCC1 antibody
      • New CC chemokine 1 antibody
      • SCYA13 antibody
      • SCYL1 antibody
      • short chain antibody
      • Small inducible cytokine A13 precursor antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 13 antibody
      • Small-inducible cytokine A13 antibody
      see all

    Anti-MCP4 antibody [500-M70] (ab9559)参考文献

    This product has been referenced in:
    • Martin P  et al. Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. Am J Pathol 179:422-35 (2011). Read more (PubMed: 21703421) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab9559.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册