概述

  • 产品名称Anti-MCP1抗体[4E2/MCP] (Biotin)
    参阅全部 MCP1 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[4E2/MCP] to MCP1 (Biotin)
  • 偶联物Biotin
  • 特异性This antibody is specific to mouse monocyte chemoattractant protein (MCP-1). The antibody does not react with related mouse beta chemokines, TCA3 and MIP-1 beta.
  • 经测试应用适用于: ELISA, ELISpotmore details
  • 种属反应性
    与反应: Mouse
    不与反应: Human
  • 免疫原

    CHO expressed, recombinant mouse MCP-1.

  • 常规说明

    The antibody was conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

性能

应用

Our Abpromise guarantee covers the use of ab21397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 1 - 4 µg/ml.
ELISpot Use at an assay dependent dilution.

靶标

  • 功能Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
  • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
  • 翻译后修饰Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C-C motif chemokine 2 antibody
    • CCL2 antibody
    • CCL2_HUMAN antibody
    • Chemokine (C C motif) ligand 2 antibody
    • GDCF 2 antibody
    • GDCF-2 antibody
    • GDCF2 antibody
    • HC11 antibody
    • HSMCR30 antibody
    • JE antibody
    • MCAF antibody
    • MCP 1 antibody
    • MCP-1 antibody
    • MCP1 antibody
    • MGC9434 antibody
    • Monocyte chemoattractant protein 1 antibody
    • Monocyte chemotactic and activating factor antibody
    • Monocyte chemotactic protein 1 antibody
    • Monocyte secretory protein JE antibody
    • SCYA2 antibody
    • Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody
    • Small inducible cytokine A2 antibody
    • Small inducible cytokine subfamily A (Cys Cys), member 2 antibody
    • Small-inducible cytokine A2 antibody
    • SMC CF antibody
    • SMC-CF antibody
    • SMCCF antibody
    see all

Anti-MCP1 antibody [4E2/MCP] (Biotin) (ab21397)参考文献

This product has been referenced in:
  • Luo Y  et al. Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1. J Immunol 153:3708-16 (1994). Read more (PubMed: 7523503) »

See 1 Publication for this product

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