概述

  • 产品名称Anti-MCP1抗体[2H5] (FITC)
    参阅全部 MCP1 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[2H5] to MCP1 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant full length mouse protein, expressed in CHO cells.

  • 阳性对照
    • LPS-activated peripheral blood mononuclear cells; thioglycolate-induced peritoneal exudate cells.

性能

应用

Our Abpromise guarantee covers the use of ab93516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 0.5µg for 105-8 cells in a total staining volume of 100µl.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
    • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
    • 翻译后修饰Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C-C motif chemokine 2 antibody
      • CCL2 antibody
      • CCL2_HUMAN antibody
      • Chemokine (C C motif) ligand 2 antibody
      • GDCF 2 antibody
      • GDCF-2 antibody
      • GDCF2 antibody
      • HC11 antibody
      • HSMCR30 antibody
      • JE antibody
      • MCAF antibody
      • MCP 1 antibody
      • MCP-1 antibody
      • MCP1 antibody
      • MGC9434 antibody
      • Monocyte chemoattractant protein 1 antibody
      • Monocyte chemotactic and activating factor antibody
      • Monocyte chemotactic protein 1 antibody
      • Monocyte secretory protein JE antibody
      • SCYA2 antibody
      • Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody
      • Small inducible cytokine A2 antibody
      • Small inducible cytokine subfamily A (Cys Cys), member 2 antibody
      • Small-inducible cytokine A2 antibody
      • SMC CF antibody
      • SMC-CF antibody
      • SMCCF antibody
      see all

    Anti-MCP1 antibody [2H5] (FITC) 图像

    • Staining of 1-day LPS-activated normal Human peripheral blood mononuclear cells with ab91516 at 0.5 ?g (blue histogram), or FITC Armenian Hamster IgG isotype control at 0.5 ?g (green histogram).
      Cells in the monocyte gate were used for analysis.

    Anti-MCP1 antibody [2H5] (FITC) (ab93516)参考文献

    This product has been referenced in:
    • Taal MW  et al. Mechanisms underlying renoprotection during renin-angiotensin system blockade. Am J Physiol Renal Physiol 280:F343-55 (2001). Read more (PubMed: 11208610) »
    • Luo Y  et al. Macrophage inflammatory protein-2 and KC induce chemokine production by mouse astrocytes. J Immunol 165:4015-23 (2000). Read more (PubMed: 11034412) »

    See all 2 Publications for this product

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