概述

  • 产品名称
  • 描述
    兔多克隆抗体to MCM7
  • 经测试应用
    适用于: IP, WBmore details
    不适用于: ICC/IF
  • 种属反应性
    与反应: Rat, Human
    不与反应: Mouse
  • 免疫原

    Synthetic peptide corresponding to residues near the N-terminus of human MCM7.

  • 阳性对照
    • HeLa cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab51062 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
WB
  • 应用说明
    IP: 1/20.
    WB: 1/5000. Detects a band of approximately 81 kDa (predicted molecular weight: 81 kDa).

    Is unsuitable for ICC/IF or IHC.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
    • 序列相似性
      Belongs to the MCM family.
      Contains 1 MCM domain.
    • 翻译后修饰
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CDABP0042 antibody
      • CDC 47 antibody
      • CDC47 antibody
      • CDC47 homolog antibody
      • Cdc47, S. cerevisiae, homolog of antibody
      • DNA replication licensing factor MCM7 antibody
      • Homolog of S. cerevisiae Cdc47 antibody
      • MCM 2 antibody
      • MCM 7 antibody
      • MCM2 antibody
      • MCM2, formerly antibody
      • Mcm7 antibody
      • MCM7 minichromosome maintenance deficient 7 antibody
      • MCM7_HUMAN antibody
      • Minichromosome Maintainence 7 antibody
      • Minichromosome maintainence, S. cerevisiae, homolog of antibody
      • Minichromosome maintenance complex component 7 antibody
      • Minichromosome maintenance deficient 7 antibody
      • Minichromosome maintenance protein 7 antibody
      • P1.1 MCM3 antibody
      • P1.1-MCM3 antibody
      • P1CDC47 antibody
      • P85MCM antibody
      • PNAS 146 antibody
      • PNAS146 antibody
      • PPP1R104 antibody
      • Protein phosphatase 1, regulatory subunit 104 antibody
      see all

    图片

    • Anti-MCM7 antibody (ab51062) at 1/5000 dilution + HeLa cell lysate at 10 µg

      Secondary
      Goat anti-Rabbit HRP labeled. at 1/2000 dilution

      Predicted band size : 81 kDa
      Observed band size : 81 kDa

    文献

    ab51062 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab51062.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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