概述
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产品名称Anti-MCF2抗体
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描述兔多克隆抗体to MCF2
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宿主Rabbit
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经测试应用适用于: WBmore details
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种属反应性与反应: Human
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免疫原
KLH conjugated synthetic peptide between 803-833 amino acids from the C-terminal region of Human MCF2 (NP_001165347.1 , NP_001165348.1 , NP_001165350.1 , NP_005360.3 ,NP_001093325.1 , NP_001165349.1).
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阳性对照
- K562 cell line lysates
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
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存储溶液Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度Immunogen affinity purified
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纯化说明Purified through a protein A column, followed by peptide affinity purification.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab112588 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | 1/100 - 1/500. Predicted molecular weight: 108 kDa. |
靶标
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相关性Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
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细胞定位Cytoplasm Isoform 1: Membrane Isoform 3: Membrane. Note: Colocalizes with CDC42 to plasma membrane.
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数据库链接
- Entrez Gene: 4168 Human
- Omim: 311030 Human
- SwissProt: P10911 Human
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别名
- DBL antibody
- DBL-transforming protein antibody
- MCF2 antibody
see all
图片
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Western blot - Anti-MCF2 antibody (ab112588)Anti-MCF2 antibody (ab112588) at 1/100 dilution + K562 cell line lysate at 35 µg
Predicted band size: 108 kDa
文献
ab112588 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"