Anti-MCF2抗体(ab112588)

概述

• 产品名称Anti-MCF2抗体
• 描述
  兔多克隆抗体to MCF2
• 经测试应用适用于: WBmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  KLH conjugated synthetic peptide between 803-833 amino acids from the C-terminal region of Human MCF2 (NP_001165347.1 , NP_001165348.1 , NP_001165350.1 , NP_005360.3 ,NP_001093325.1 , NP_001165349.1).

• 阳性对照
  • K562 cell line lysates

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
• 存储溶液Preservative: 0.09% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• 纯度Immunogen affinity purified
• 纯化说明Purified through a protein A column, followed by peptide affinity purification.
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Signal Transduction
  • Signaling Pathway
  • G Protein Signaling
  • Small G Proteins
  • Regulators

  • Cancer
  • Oncoproteins/suppressors
  • Oncoproteins
  • Signal transducers

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 相关性Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
• 细胞定位Cytoplasm Isoform 1: Membrane Isoform 3: Membrane. Note: Colocalizes with CDC42 to plasma membrane.
• 数据库链接
  • Entrez Gene: 4168 Human
  • Omim: 311030 Human
  • SwissProt: P10911 Human
• 别名
  • DBL antibody
  • DBL-transforming protein antibody
  • MCF2 antibody

  • MCF2-transforming protein antibody
  • Proto-oncogene DBL antibody
  • Proto-oncogene MCF-2 antibody

  see all