概述

  • 产品名称Anti-MCC抗体
    参阅全部 MCC 一抗
  • 描述
    小鼠单克隆抗体to MCC
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: DIVELNKRLQ QTERERDLLE KKLAKAQCEQ SHLMREHEDV QERTTLRYEE RITELHSVIA ELNKKIDRLQ GTTIREEDEY SELRSELSQS QHEVNEDSRS , corresponding to amino acids 31-130 of Human MCC

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab55489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.
    • 组织特异性Expressed in a variety of tissues.
    • 序列相似性Belongs to the MCC family.
    • 细胞定位Cell membrane. Nucleus. Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Colorectal mutant cancer protein antibody
      • CRCM_HUMAN antibody
      • DKFZp762O1615 antibody
      • FLJ38893 antibody
      • FLJ46755 antibody
      • MCC 1 antibody
      • MCC antibody
      • MCC1 antibody
      • Mutated in colorectal cancers antibody
      • Protein MCC antibody
      see all

    Anti-MCC antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab55489 MCC antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-MCC antibody (ab55489)参考文献

    ab55489 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"