Anti-MC2 receptor抗体(ab77347)

概述

  • 产品名称Anti-MC2 receptor抗体
    参阅全部 MC2 receptor 一抗
  • 描述
    山羊多克隆抗体to MC2 receptor
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Sheep, Horse, Cow, Dog, Chimpanzee
  • 免疫原

    Synthetic peptide:

    ENINNTARNNSDC

    , corresponding to N terminal amino acids 9-21 of Human MC2 receptor (NP_000520.1)

  • 阳性对照
    • Human skin lysate.

性能

应用

Our Abpromise guarantee covers the use of ab77347 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Peptide ELISA: Antibody detection limit dilution: 1/32000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 34 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase.
    • 组织特异性Melanocytes and corticoadrenal tissue.
    • 疾病相关Defects in MC2R are the cause of glucocorticoid deficiency type 1 (GCCD1) [MIM:202200]; also known as familial glucocorticoid deficiency type 1 (FGD1). GCCD1 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency.
    • 序列相似性Belongs to the G-protein coupled receptor 1 family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ACTH receptor antibody
      • ACTH-R antibody
      • ACTHR antibody
      • ACTHR_HUMAN antibody
      • Adrenocorticotropic hormone receptor antibody
      • Adrenocorticotropin receptor antibody
      • Corticotropin receptor antibody
      • MC2 receptor antibody
      • MC2-R antibody
      • MC2R antibody
      • Melanocortin 2 receptor (adrenocorticotropic hormone) antibody
      • Melanocortin 2 receptor antibody
      • Melanocortin receptor 2 antibody
      see all

    Anti-MC2 receptor antibody 图像

    Anti-MC2 receptor antibody (ab77347)参考文献

    ab77347 has not yet been referenced specifically in any publications.

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