概述

  • 产品名称Anti-MBD5抗体
    参阅全部 MBD5 一抗
  • 描述
    兔多克隆抗体to MBD5
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Human
  • 免疫原

    A synthetic peptide corresponding to C-terminal residues of human MBD5

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 160 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro).
  • 组织特异性Detected in heart, placenta, liver, skeletal muscle, kidney and pancreas.
  • 疾病相关Defects in MBD5 are the cause of mental retardation autosomal dominant type 1 (MRD1) [MIM:156200]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.
  • 序列相似性Contains 1 MBD (methyl-CpG-binding) domain.
    Contains 1 PWWP domain.
  • 结构域Both MBD and PWWP domains are necessary for chromocentric localization.
  • 细胞定位Nucleus. Chromosome. Associated with pericentric heterochromatin and Nucleus. Not associated with pericentric heterochromatin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9430004D19Rik antibody
    • AA536666 antibody
    • AI426407 antibody
    • C030040A15Rik antibody
    • FLJ11113 antibody
    • FLJ30517 antibody
    • KIAA1461 antibody
    • MBD5 antibody
    • MBD5_HUMAN antibody
    • methyl CpG binding domain protein 5 antibody
    • Methyl CpG binding protein MBD5 antibody
    • Methyl-CpG-binding domain protein 5 antibody
    • Methyl-CpG-binding protein MBD5 antibody
    • RP23 167N13.1 antibody
    see all

Anti-MBD5 antibody (ab56126)参考文献

ab56126 has not yet been referenced specifically in any publications.

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