MBD2 Binding Activity Quantification Assay试剂盒(ab113473)

概述

  • 产品名称MBD2 Binding Activity Quantification Assay试剂盒
  • 检测类型Quantitative
  • 检测时间
    3h 00m
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: all Mammals
  • 产品概述

    MBD2 (methyl-CpG binding domain protein 2) belongs to a family of MBD domain containing proteins. This family of proteins associates with heterochromatin by their interaction with methylated DNA at CpG islands, and appear to 'read' and 'translate' the DNA methylation signal into transcriptional repression by recruiting silencing complexes and histone deacetylases among other proteins. MBD2 is the methyl-binding component of the MeCP1 complex, which allows MBD2 to target HDAC/chromatin remodeling activity to methylated templates.

     MBD2 Binding Activity Quantification Assay Kit (ab113473) allows the user to measure binding activity of MBD2 to methylated DNA in human cells/tissues. It can also be used to determine inhibitors of MBD2 activity.

  • 经测试应用适用于: Functional Studiesmore details

性能

    应用

    Our Abpromise guarantee covers the use of ab113473 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    应用 Ab评论 说明
    Functional Studies Use at an assay dependent concentration.

    实验方案

    MBD2 Binding Activity Quantification Assay Kit (ab113473)参考文献

    ab113473 has not yet been referenced specifically in any publications.

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