概述

  • 产品名称Anti-Matrix protein 1抗体(HRP)
    参阅全部 Matrix protein 1 一抗
  • 描述
    山羊多克隆抗体to Matrix protein 1 (HRP)
  • 偶联物HRP
  • 特异性Ab21008 recognizes the matrix protein (M) for any strain of Influenza A. Conservation of the matrix protein sequence between hemagluttinin/Neuraminidase typed strains. Does not react with HEp-2 cells by indirect immunofluorescence.
  • 经测试应用适用于: ELISA, ICC/IF, WBmore details
    不适用于: IHC
  • 种属反应性
    Does not react with Influenza B, Adenovirus, Respiratory syncytial virus and Parainfluenza viruses (1-3). Not yet tested in other species.
  • 免疫原

    corresponding to Matrix protein 1. Purified M1 protein, Influenza A-Phillipines (H3N2).

  • 常规说明

    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

    The antibody is covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.

性能

应用

Our Abpromise guarantee covers the use of ab21008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.
WB Use a concentration of 1 µg/ml.
  • 应用说明Is unsuitable for IHC.
  • 靶标

    • 相关性Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions.
    • 细胞定位Cytoplasmic
    • 别名
      • M1 antibody
      • Matrix Protein 1 antibody
      • Matrix Protein I antibody
      • Membrane matrix protein M1 antibody

    Anti-Matrix protein 1 antibody (HRP) (ab21008)参考文献

    This product has been referenced in:
    • Poon LL  et al. Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice. J Immunol 182:3063-71 (2009). WB . Read more (PubMed: 19234203) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"