Anti-Mast Cell Chymase抗体(ab123510)

概述

  • 产品名称Anti-Mast Cell Chymase抗体
    参阅全部 Mast Cell Chymase 一抗
  • 描述
    山羊多克隆抗体to Mast Cell Chymase
  • 经测试应用适用于: IHC, ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cynomolgus Monkey
  • 免疫原

    Synthetic peptide corresponding to Human Mast Cell Chymase aa 96-110 (internal sequence).
    Sequence:

    C-QFRHPKYNTSTLHHD


    Database link: P23946

  • 阳性对照
    • HEK293 lysate transiently expressing full-length Human Mast Cell Chymase

性能

应用

Our Abpromise guarantee covers the use of ab123510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC Use a concentration of 2 - 4 µg/ml.
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:128,000.

WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 27 kDa.

靶标

  • 功能Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
  • 组织特异性Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions.
  • 序列相似性Belongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • 细胞定位Secreted. Cytoplasmic granule. Mast cell granules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha-chymase antibody
    • Chymase 1 antibody
    • Chymase 1 mast cell antibody
    • chymase 1 preproprotein transcript E antibody
    • chymase 1 preproprotein transcript I antibody
    • Chymase antibody
    • Chymase, heart antibody
    • Chymase, mast cell antibody
    • CMA1 antibody
    • CMA1_HUMAN antibody
    • CYH antibody
    • CYM antibody
    • EC 3.4.21.39 antibody
    • Mast cell chymase 1 antibody
    • Mast cell protease 3 antibody
    • Mast cell protease 5 antibody
    • Mast cell protease I antibody
    • Mast cell protease III antibody
    • Mcp-5 antibody
    • MCP3P antibody
    • Mcpt5 antibody
    • MCT1 antibody
    • MGC119890 antibody
    • MGC119891 antibody
    • MMCP-5 antibody
    see all

Anti-Mast Cell Chymase antibody 图像

  • Immunohistochemical analysis of paraffin embedded Human Skin tissue labeling Mast Cell Chymase with ab123510 at 2 ug/ml. Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). The HRP-staining procedure was used for detection.

  • Lane 1 : Anti-Mast Cell Chymase antibody (ab123510) at 0.5 µg/ml
    Lane 2 : Anti-Mast Cell Chymase antibody (ab123510) at 1 mg/ml
    Lane 3 : Anti-tag antibody at 1/3000 dilution

    Lane 1 : HEK293 lysate over expressing Human CMA1 with a tag at 10 µg
    Lane 2 : Mock-transfected HEK293 lysate
    Lane 3 : HEK293 lysate over expressing Human CMA1 with a tag at 10 µg

    Developed using the ECL technique

    Predicted band size : 27 kDa

Anti-Mast Cell Chymase antibody (ab123510)参考文献

ab123510 has not yet been referenced specifically in any publications.

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The immunogen sequence of antibody ab2377 is Purified human skin Chymase, ab111239, Human testis and tonsil tissue and ab54176 is Purified human skin chymase.

We unfortunately do not have any extra immu...

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