Anti-MAS1抗体(ab123326)

概述

  • 产品名称Anti-MAS1抗体
    参阅全部 MAS1 一抗
  • 描述
    兔多克隆抗体to MAS1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 284-314 of Human MAS1 (NP_002368.1).

  • 阳性对照
    • CEM cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab123326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 37 kDa.

靶标

  • 功能Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
  • 疾病相关The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MAS antibody
    • MAS proto oncogene antibody
    • Mas-related G protein-coupled receptor A antibody
    • MAS_HUMAN antibody
    • Mas1 antibody
    • MAS1 oncogene antibody
    • MAS1 proto-oncogene, G protein-coupled receptor antibody
    • MGRA antibody
    • Proto-oncogene Mas antibody
    see all

Anti-MAS1 antibody 图像

  • Anti-MAS1 antibody (ab123326) at 1/100 dilution + CEM cell line lysates at 35 µg

    Predicted band size : 37 kDa

Anti-MAS1 antibody (ab123326)参考文献

ab123326 has not yet been referenced specifically in any publications.

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