概述

  • 产品名称Anti-MARVELD2抗体
  • 描述
    兔多克隆抗体to MARVELD2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of Human MARVELD2 (NP_001033692.1).

  • 阳性对照
    • MDA-MB231 cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab95358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 64 kDa.

靶标

  • 功能Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.
  • 疾病相关Defects in MARVELD2 are the cause of deafness autosomal recessive type 49 (DFNB49) [MIM:610153]. DFNB49 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • 序列相似性Contains 1 MARVEL domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cell membrane. Cell junction > tight junction. Found at tricellular contacts.
  • Information by UniProt
  • 数据库链接
  • 别名
    • deafness, autosomal recessive 49 antibody
    • DFNB49 antibody
    • MALD2_HUMAN antibody
    • MARVD2 antibody
    • MARVEL (membrane-associating) domain containing 2 antibody
    • MARVEL domain containing protein 2 antibody
    • MARVEL domain-containing protein 2 antibody
    • Marveld2 antibody
    • TRIC antibody
    • Tricellulin antibody
    see all

Anti-MARVELD2 antibody 图像

  • Anti-MARVELD2 antibody (ab95358) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µg

    Predicted band size : 64 kDa

Anti-MARVELD2 antibody (ab95358)参考文献

ab95358 has not yet been referenced specifically in any publications.

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