Anti-MARCKS抗体(ab78885)

概述

  • 产品名称Anti-MARCKS抗体
    参阅全部 MARCKS 一抗
  • 描述
    兔多克隆抗体to MARCKS
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic non-phosphopeptide derived from Human MARCKS around the phosphorylation site of serine 158 (R-F-SP-F-K).

  • 阳性对照
    • WB: extracts from Mouse brain cells. ICC/IF: A549 cells.

性能

应用

Our Abpromise guarantee covers the use of ab78885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 32 kDa.
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
  • 序列相似性Belongs to the MARCKS family.
  • 翻译后修饰Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.
  • 细胞定位Cytoplasm > cytoskeleton. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 80 kDa protein antibody
    • 80K L antibody
    • 80K L protein antibody
    • 80K-L protein antibody
    • 80KL antibody
    • 81 kDa protein, light chain antibody
    • light chain antibody
    • MACS antibody
    • MARCKS antibody
    • MARCS antibody
    • MARCS_HUMAN antibody
    • MGC52672 antibody
    • myristoylated alanine rich C kinase substrate antibody
    • Myristoylated alanine rich protein kinase C substrate (MARCKS, 80K L) antibody
    • Myristoylated alanine rich protein kinase C substrate antibody
    • Myristoylated alanine-rich C-kinase substrate antibody
    • Phosphomyristin antibody
    • PKCSL antibody
    • PRKCSL antibody
    • protein kinase C substrate 80 kDa protein light chain antibody
    • Protein kinase C substrate antibody
    see all

Anti-MARCKS antibody 图像

  • All lanes : Anti-MARCKS antibody (ab78885) at 1/500 dilution

    Lane 1 : Extracts from Mouse brain cells
    Lane 2 : Extracts from Mouse brain cells with immunizing peptide at 5 µg

    Lysates/proteins at 20 µg per lane.


    Predicted band size : 32 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • Left: immunofluorescence analysis of A549 cells using ab78885 at 1/500 dilution. Right: same, after pre-treatment with immunizing peptide.

Anti-MARCKS antibody (ab78885)参考文献

ab78885 has not yet been referenced specifically in any publications.

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These antibodies will bind to the total protein (phospho and non-phospho).

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"