This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

概述

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab77417 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunising peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

  • 应用说明Peptide ELISA: Antibody detection limit dilution 1/4000.
    WB: Preliminary experiments in Human Brain (Amygdala, Cerebellum, Cerebral Cortex, Frontal Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). Predicted molecular weight: 46 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
    • 细胞定位Golgi apparatus membrane; Multipass membrane protein.
    • 数据库链接
    • 别名
      • BC056494 antibody
      • E3 ubiquitin protein ligase MARCH4 antibody
      • KIAA1399 antibody
      • MARCH 4 antibody
      • MARCH IV antibody
      • Membrane associated RING CH protein IV antibody
      • Membrane associated ring finger (C3HC4) 4 antibody
      • Membrane associated RING finger protein 4 antibody
      • MGC104908 antibody
      • mKIAA1399 antibody
      • RING finger protein 174 antibody
      • RNF174 antibody
      see all

    Anti-MARCH4 antibody (ab77417)参考文献

    ab77417 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"