Anti-MAPK11抗体- Carboxyterminal end (ab37937)

概述

  • 产品名称
    Anti-MAPK11抗体- Carboxyterminal end
    参阅全部 MAPK11 一抗
  • 描述
    兔多克隆抗体to MAPK11 - Carboxyterminal end
  • 经测试应用
    适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide, selected from C terminal amino acids 356-372 of human MAPK11.

  • 阳性对照
    • Human placenta lysate, and human breast carcinoma and human hepatocarcinoma tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    Eluted out with both high and low pH buffers and neutralized immediately after elution, followed by dialysis against PBS.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab37937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 42 kDa.
IHC-P 1/50 - 1/100.

靶标

  • 功能
    Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2.
  • 组织特异性
    Highest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 序列相似性
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • 结构域
    The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • 翻译后修饰
    Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Human p38Beta MAP kinase mRNA complete cds antibody
    • MAP kinase 11 antibody
    • MAP kinase p38 beta antibody
    • MAPK 11 antibody
    • Mapk11 antibody
    • Mitogen activated protein kinase 11 antibody
    • Mitogen activated protein kinase p38 2 antibody
    • Mitogen activated protein kinase p38 beta antibody
    • Mitogen-activated protein kinase 11 antibody
    • Mitogen-activated protein kinase p38 beta antibody
    • MK11_HUMAN antibody
    • p38 2 antibody
    • p38-2 antibody
    • p38B antibody
    • p38Beta antibody
    • P38BETA2 antibody
    • PRKM11 antibody
    • Protein kinase mitogen activated 11 antibody
    • SAPK2 antibody
    • SAPK2B antibody
    • Stress activated protein kinase 2 antibody
    • Stress activated protein kinase 2b antibody
    • Stress-activated protein kinase 2 antibody
    see all

图片

  • Anti-MAPK11 antibody - Carboxyterminal end (ab37937) at 1/100 dilution + Human placenta lysate

    Observed band size : 42 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labeling MAPK11 with ab37937 at a 1/50 dilution.

     

文献

ab37937 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab37937.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册