概述

  • 产品名称Anti-MAP4K4抗体
    参阅全部 MAP4K4 一抗
  • 描述
    兔多克隆抗体to MAP4K4
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide from a region within N terminal amino acids 288-337 (FIRDQPNERQ VRIQLKDHID RTRKKRGEKD ETEYEYSGSE EEEEEVPEQE) of Human MAP4K4 (NP_004825)

  • 阳性对照
    • Human fetal small intestine lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab90292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 142 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway.
  • 组织特异性Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CNH domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLH21957 antibody
    • FLJ10410 antibody
    • FLJ20373 antibody
    • FLJ90111 antibody
    • Hepatocyte progenitor kinase like/germinal center kinase like kinase antibody
    • HGK antibody
    • HPK/GCK like kinase antibody
    • HPK/GCK like kinase HGK antibody
    • HPK/GCK-like kinase HGK antibody
    • KIAA0687 antibody
    • M4K4_HUMAN antibody
    • MAP4K4 antibody
    • MAPK/ERK kinase kinase kinase 4 antibody
    • MEK kinase kinase 4 antibody
    • MEKKK 4 antibody
    • MEKKK4 antibody
    • Mitogen activated protein kinase kinase kinase kinase 4 antibody
    • Mitogen-activated protein kinase kinase kinase kinase 4 antibody
    • Nck interacting kinase antibody
    • Nck-interacting kinase antibody
    • NIK antibody
    see all

Anti-MAP4K4 antibody 图像

  • Anti-MAP4K4 antibody (ab90292) at 1 µg/ml + Human fetal small intestine lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 142 kDa
    Gel concentration: 6-18%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver tissue labelling MAP4K4 with ab90292 at 4-8µg/ml.

Anti-MAP4K4 antibody (ab90292)参考文献

ab90292 has not yet been referenced specifically in any publications.

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