概述

  • 产品名称
  • 描述
    兔多克隆抗体to MAP4
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to C terminal residues of MAP4 (Human)

性能

应用

Our Abpromise guarantee covers the use of ab94401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 121 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/2000 - 1/5000.

靶标

  • 功能
    Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
  • 序列相似性
    Contains 4 Tau/MAP repeats.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338.
  • 细胞定位
    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp779A1753 antibody
    • MAP-4 antibody
    • MAP4 antibody
    • MAP4_HUMAN antibody
    • MGC8617 antibody
    • Microtubule associated protein 4 antibody
    • Microtubule-associated protein 4 antibody
    • OTTHUMP00000210723 antibody
    • OTTHUMP00000210725 antibody
    • OTTHUMP00000210727 antibody
    • OTTHUMP00000210730 antibody
    see all

实验方案

文献

ab94401 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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