重组
RabMAb

Anti-MAP3K8抗体[EP1103Y] (ab52613)

概述

  • 产品名称
    Anti-MAP3K8抗体[EP1103Y]
    参阅全部 MAP3K8 一抗
  • 描述
    兔单克隆抗体[EP1103Y] to MAP3K8
  • 经测试应用
    适用于: WBmore details
    不适用于: Flow Cyt,ICC/IF,IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Jurkat cell lysate
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab52613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Predicted molecular weight: 53 kDa.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • 靶标

    • 功能
      Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein.
    • 组织特异性
      Expressed in several normal tissues and human tumor-derived cell lines.
    • 序列相似性
      Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
      Contains 1 protein kinase domain.
    • 发展阶段
      Isoform 1 is activated specifically during the S and G2/M phases of the cell cycle.
    • 翻译后修饰
      Autophosphorylated. Isoform 1 undergoes phosphorylation mainly on Ser residues, and isoform 2 on both Ser and Thr residues.
    • 细胞定位
      Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AURA2 antibody
      • c COT antibody
      • Cancer Osaka thyroid oncogene antibody
      • CCOT antibody
      • COT antibody
      • COT proto oncogene serine/threonine protein kinase antibody
      • EST antibody
      • ESTF antibody
      • Ewing sarcoma transformant antibody
      • FLJ10486 antibody
      • M3K8_HUMAN antibody
      • MAP3K 8 antibody
      • MAP3K8 antibody
      • MEKK8 antibody
      • Mitogen activated protein kinase kinase kinase 8 antibody
      • Mitogen-activated protein kinase kinase kinase 8 antibody
      • Proto oncogene cCot antibody
      • Proto-oncogene c-Cot antibody
      • Serine/threonine protein kinase cot antibody
      • Serine/threonine-protein kinase cot antibody
      • TPL 2 antibody
      • TPL-2 antibody
      • TPL2 antibody
      • Tumor progression locus 2 antibody
      see all

    图片

    • Anti-MAP3K8 antibody [EP1103Y] (ab52613) at 1/500 dilution + Jurkat cell lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP antibody at 1/2000 dilution

      Predicted band size : 53 kDa
      Observed band size : 53 kDa

    文献

    ab52613 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab52613.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册