RabMAb

Anti-MAP3K4抗体[EP551Y] (ab40784)

概述

  • 产品名称Anti-MAP3K4抗体[EP551Y]
    参阅全部 MAP3K4 一抗
  • 描述
    兔单克隆抗体[EP551Y] to MAP3K4
  • 特异性This antibody is predicted to detect splice isoform 2 based on sequence analysis.
  • 经测试应用适用于: IHC-P, ICC, Flow Cyt, WBmore details
    不适用于: IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human MAP3K4 aa 150-250.
    Database link: Q9Y6R4

  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    A trial size is available to purchase for this antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Alternative versions available:

    Anti-MEK4 antibody (Alexa Fluor® 488) [EP551Y] (ab200611)

    Anti-MEK4 antibody (Alexa Fluor® 647) [EP551Y] (ab200522)

性能

应用

Our Abpromise guarantee covers the use of ab40784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ICC 1/100 - 1/250.
Flow Cyt 1/20.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

WB 1/1000 - 1/5000. Detects a band of approximately 200 kDa (predicted molecular weight: 182 kDa).
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
    • 组织特异性Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.
    • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
      Contains 1 protein kinase domain.
    • 细胞定位Cytoplasm > perinuclear region. Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles.
    • Information by UniProt
    • 数据库链接
    • 别名
      • dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody
      • FLJ42439 antibody
      • KIAA0213 antibody
      • M3K4_HUMAN antibody
      • MAP three kinase 1 antibody
      • MAP/ERK kinase kinase 4 antibody
      • MAP3K4 antibody
      • MAPK/ERK kinase kinase 4 antibody
      • MAPKKK4 antibody
      • MEK kinase 4 antibody
      • MEKK 4 antibody
      • MEKK4 antibody
      • Mitogen-activated protein kinase kinase kinase 4 antibody
      • MTK1 antibody
      • predicted protein of HQ0412 antibody
      • PRO0412 antibody
      • RP3-473J16.4 antibody
      • SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of antibody
      see all

    Anti-MAP3K4 antibody [EP551Y] 图像

    • Anti-MAP3K4 antibody [EP551Y] (ab40784) at 1/1000 dilution + 293 cell lysate. at 10 µg

      Predicted band size : 182 kDa
      Observed band size : 200 kDa (why is the actual band size different from the predicted?)
    • Immunohistochemical analysis of paraffin-embedded human ovary adenocarcinoma using ab40784.

    Anti-MAP3K4 antibody [EP551Y] (ab40784)参考文献

    ab40784 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"