概述

  • 产品名称Anti-MAP3K4抗体
    参阅全部 MAP3K4 一抗
  • 描述
    兔多克隆抗体to MAP3K4
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence at C-terminal of Human MAP3K4.

  • 阳性对照
    • Human heart tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab110891 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110891 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
  • 组织特异性Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位Cytoplasm > perinuclear region. Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody
    • FLJ42439 antibody
    • KIAA0213 antibody
    • M3K4_HUMAN antibody
    • MAP three kinase 1 antibody
    • MAP/ERK kinase kinase 4 antibody
    • MAP3K4 antibody
    • MAPK/ERK kinase kinase 4 antibody
    • MAPKKK4 antibody
    • MEK kinase 4 antibody
    • MEKK 4 antibody
    • MEKK4 antibody
    • Mitogen-activated protein kinase kinase kinase 4 antibody
    • MTK1 antibody
    • predicted protein of HQ0412 antibody
    • PRO0412 antibody
    • RP3-473J16.4 antibody
    • SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of antibody
    see all

Anti-MAP3K4 antibody 图像

  • ab110891, at a 1/50 dilution, staining MAP3K4 in paraffin-embedded Human heart tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-MAP3K4 antibody (ab110891)参考文献

ab110891 has not yet been referenced specifically in any publications.

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