概述

  • 产品名称Anti-MAP3K13抗体
    参阅全部 MAP3K13 一抗
  • 描述
    兔多克隆抗体to MAP3K13
  • 特异性 ab113034 recognises isoform 3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human) conjugated to KLH selected from the C-terminal region surrounding S869 of Human MAP3K13 protein.

  • 阳性对照
    • Human brain tissue and CEM cell line lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明 ab113034 was purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab113034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 98 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
  • 组织特异性Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated on serine and threonine residues.
  • 细胞定位Cytoplasm. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.7.11.25 antibody
    • Leucine zipper bearing kinase antibody
    • Leucine zipper-bearing kinase antibody
    • LZK antibody
    • M3K13_HUMAN antibody
    • MAP3K13 antibody
    • MEKK13 antibody
    • MGC133196 antibody
    • Mitogen activated protein kinase kinase kinase 13 antibody
    • Mitogen-activated protein kinase kinase kinase 13 antibody
    • Mixed lineage kinase antibody
    • MLK antibody
    • OTTHUMP00000210397 antibody
    see all

Anti-MAP3K13 antibody 图像

  • Anti-MAP3K13 antibody (ab113034) at 1/100 dilution + CEM cell line lysates at 35 µg

    Predicted band size : 98 kDa
  • Formalin-fixed and paraffin-embedded Human brain tissue tissue reacted with ab113034 at 1/10, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-MAP3K13 antibody (ab113034)参考文献

ab113034 has not yet been referenced specifically in any publications.

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