兔单克隆抗体[EPR2361] to MAP2 (phospho S136)
Mouse, Rat, Human
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human MAP2 (phospho S136).
WB: Human fetal brain and mouse brain tissue lysates
IHC-P: Human brain tissue
This product is a recombinant rabbit monoclonal antibody.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 200 kDa.
1/10 - 1/100.
1/100 - 1/250.
Is unsuitable for Flow Cyt.
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Contains 3 Tau/MAP repeats.
Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67.
Information by UniProt
MAP 2 antibody
MAP dendrite specific antibody
Western blot - MAP2 (phospho S136) antibody [EPR2361] (ab96378)
All lanes : Anti-MAP2 (phospho S136) antibody [EPR2361] (ab96378) at 1/1000 dilution Lane 1 : Untreated fetal brain lysates Lane 2 : Fetal brain lysates treated with Alkaline Phosphatase Lane 3 : Mouse brain lysates Lysates/proteins at 10 µg per lane. Secondary HRP/AP polymerized antibody Predicted band size : 200 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MAP2 (phospho S136) antibody [EPR2361] (ab96378)
ab96378, at a 1/100 dilution, staining MAP2 in paraffin embedded Human brain tissue by Immunohistochemical analysis.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"