概述

  • 产品名称Anti-MAP1抗体
    参阅全部 MAP1 一抗
  • 描述
    兔多克隆抗体to MAP1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to 15 internal sequence amino acids from Human MAP1.

  • 阳性对照
    • Human brain (cortex) tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -80°C.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
  • 组织特异性Ubiquitously expressed with higher levels in heart and brain.
  • 序列相似性Belongs to the PNMA family.
  • 结构域The BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MAP 1 antibody
    • MAP-1 antibody
    • MAP1 antibody
    • MOAP1 antibody
    • MOAP1_HUMAN antibody
    • Modulator of apoptosis 1 antibody
    • Modulator of Apoptosis antibody
    • Paraneoplastic antigen like 4 antibody
    • Paraneoplastic antigen Ma4 antibody
    • paraneoplastic Ma antigen family member 4 antibody
    • PNMA4 antibody
    see all

Anti-MAP1 antibody 图像

  • ab115511 at 2.5ug/ml staining MAP1 in Human brain (cortex) tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-MAP1 antibody (ab115511)参考文献

ab115511 has not yet been referenced specifically in any publications.

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