Anti-Mannan Binding Lectin抗体[6B11] (ab23479)

概述

  • 产品名称
    Anti-Mannan Binding Lectin抗体[6B11]
    参阅全部 Mannan Binding Lectin 一抗
  • 描述
    小鼠单克隆抗体[6B11] to Mannan Binding Lectin
  • 经测试应用
    适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Chicken
  • 免疫原

    Full length native protein purified from plasma (Chicken).

  • 常规说明


    This antibody can be used as coating antibody and as detection antibody in a sandwich ELISA on chicken plasma or serum.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein A purified
  • Primary antibody说明
    This antibody can be used as coating antibody and as detection antibody in a sandwich ELISA on chicken plasma or serum.
  • 克隆
    单克隆
  • 克隆编号
    6B11
  • 骨髓瘤
    x63-Ag8.653
  • 同种型
    IgG1
  • 轻链类型
    lambda
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/4000.
WB 1/1000. Predicted molecular weight: 26 kDa.
IHC-P 1/50.

靶标

  • 功能
    Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
  • 组织特异性
    Plasma protein produced mainly in the liver.
  • 疾病相关
    Note=There is an association between low levels of MBL2 and a defect of opsonization which results in susceptibility to frequent and chronic infections.
  • 序列相似性
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 别名
    • COLEC 1 antibody
    • COLEC1 antibody
    • Collectin-1 antibody
    • HSMBPC antibody
    • Lectin, mannose-binding, soluble, 2 antibody
    • Mannan binding lectin antibody
    • Mannan binding protein antibody
    • Mannan-binding protein antibody
    • Mannose binding lectin (protein C) 2 soluble antibody
    • Mannose binding lectin (protein C) 2, soluble (opsonic defect) antibody
    • Mannose binding lectin (protein C) 2, soluble antibody
    • Mannose binding lectin 2 soluble antibody
    • Mannose binding lectin 2, soluble (opsonic defect) antibody
    • Mannose binding lectin antibody
    • Mannose binding lectin protein C2 soluble opsonic defect antibody
    • Mannose binding protein antibody
    • Mannose binding protein C antibody
    • Mannose binding protein C precursor antibody
    • Mannose binding protein, serum antibody
    • Mannose-binding lectin antibody
    • Mannose-binding protein C antibody
    • MBL 2 antibody
    • MBL antibody
    • MBL2 antibody
    • MBL2_HUMAN antibody
    • MBL2D antibody
    • MBP 1 antibody
    • MBP antibody
    • MBP C antibody
    • MBP-C antibody
    • MBP1 antibody
    • MBPB antibody
    • MBPC antibody
    • MBPD antibody
    • MGC116832 antibody
    • MGC116833 antibody
    • Opsonic defect antibody
    • protein C antibody
    • Soluble mannose binding lectin antibody
    see all

文献

ab23479 has not yet been referenced specifically in any publications.

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