Anti-Malondialdehyde抗体(FITC) (ab27615)

概述

  • 产品名称Anti-Malondialdehyde抗体(FITC)
    参阅全部 Malondialdehyde 一抗
  • 描述
    山羊多克隆抗体to Malondialdehyde (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性thsi antibody specifically binds to Malondialdehyde.
  • 经测试应用适用于: ICC/IFmore details
  • 免疫原

    Chemical/ Small Molecule MDA modified protein

  • 常规说明

    Molar FITC/ Protein ratio is 3.1

性能

应用

Our Abpromise guarantee covers the use of ab27615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent dilution.

靶标

  • 相关性Malondialdehyde (MDA) is a natural product formed in all mammalian cells as a product of lipid peroxidation. MDA is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G which appears to be a major endogenous DNA adduct in human beings that may contribute significantly to cancer linked to lifestyle and dietary factors. MDA modified proteins may show altered physico chemical behavior and antigenicity. MDA is toxic and has been implicated in aging mutagenesis, carcinogenesis, diabetic nephropathy and radiation damage. Increased expression of MDA has been reported in the brains of Alzheimer's patients. Antibodies to MDA will help to visualize the MDA adducts.
  • 别名
    • 1133 Tetramethoxypropane antibody
    • MDA antibody

Anti-Malondialdehyde antibody (FITC) (ab27615)参考文献

ab27615 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 21°C
Antigen retrieval step None
Sample Rat Tissue sections (Rat Forebrain)
Specification Rat Forebrain
Permeabilization No
Fixative Paraformaldehyde
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提交于 Oct 23 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"