概述

  • 产品名称Anti-MAL2抗体
    参阅全部 MAL2 一抗
  • 描述
    兔多克隆抗体to MAL2
  • 经测试应用适用于: ELISA, ICC, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the N-terminal domain of human MAL2

性能

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应用

Our Abpromise guarantee covers the use of ab75347 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
ICC 1/50 - 1/200.
WB 1/200 - 1/1000. Predicted molecular weight: 19 kDa.

靶标

  • 功能Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway.
  • 组织特异性Predominantly expressed in kidney, lung, and liver. Also found in thyroid gland, stomach and, at lower levels in testis and small intestine.
  • 序列相似性Belongs to the MAL family.
    Contains 1 MARVEL domain.
  • 细胞定位Cell membrane. Apical cell membrane. Endomembrane system. Cytoplasm > perinuclear region. Associated with lipid rafts. In polarized epithelial cells, restricted to the apical surface. In hepatocytes, as well as in polarized hepatoma HepG2 cells, found in the canalicular membrane, equivalent to the apical surface, beneath the canalicular actin cytoskeleton. In non-polarized HepG2 cells, distributed to the perinuclear region.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MAL 2 antibody
    • MAL proteolipid protein 2 antibody
    • Mal, T cell differentiation protein 2 antibody
    • mal2 antibody
    • MAL2_HUMAN antibody
    • Protein MAL2 antibody
    see all

Anti-MAL2 antibody (ab75347)参考文献

This product has been referenced in:
  • Katz E  et al. An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer. PLoS One 6:e17083 (2011). WB . Read more (PubMed: 21347235) »

See 1 Publication for this product

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