概述

  • 产品名称Anti-MAGEE1抗体
    参阅全部 MAGEE1 一抗
  • 描述
    兔多克隆抗体to MAGEE1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within N-terminal amino acids 102-151 (SCCSSFSWSS FSEESSSQKG EDTGTCQGLP DSESSFTYTL DEKVAELVEF) of Human MAGEE1 (NP_057333).

  • 阳性对照
    • 721_B cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab111361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 组织特异性Not expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non-small cell lung cancer and liver cancer. In hepatocellular carcinoma, there is a inverse correlation between tumor differentiation and protein expression, i.e. the lower the differentiation, the higher percentage of expression.
  • 序列相似性Contains 1 MAGE domain.
  • 发展阶段Strongly expressed in spermatogonia and primary spermatocytes. At later stages of maturation, expression gradually decreases and becomes undetectable in mature spermatids.
  • 细胞定位Cytoplasm. Nucleus. Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cancer testis antigen 10 antibody
    • Cancer/testis antigen 10 antibody
    • CT10 antibody
    • HCA587 antibody
    • Hepatocellular cancer antigen 587 antibody
    • Hepatocellular carcinoma associated antigen 587 antibody
    • Hepatocellular carcinoma-associated antigen 587 antibody
    • MAGC2_HUMAN antibody
    • MAGE C2 antigen antibody
    • MAGE E1 antigen antibody
    • MAGE family member C2 antibody
    • MAGE-C2 antigen antibody
    • MAGE-E1 antigen antibody
    • MAGEC2 antibody
    • Melanoma antigen family C 2 antibody
    • Melanoma antigen family C2 antibody
    • Melanoma antigen family E 1 cancer/testis specific antibody
    • Melanoma associated antigen C2 antibody
    • Melanoma-associated antigen C2 antibody
    • MGC13377 antibody
    see all

Anti-MAGEE1 antibody 图像

  • Anti-MAGEE1 antibody (ab111361) at 1 µg/ml + 721_B cell lysate at 10 µg

    Predicted band size : 41 kDa

Anti-MAGEE1 antibody (ab111361)参考文献

ab111361 has not yet been referenced specifically in any publications.

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