Anti-MAGEA10抗体- Carboxyterminal end (ab71788)

概述

  • 产品名称Anti-MAGEA10抗体- Carboxyterminal end
    参阅全部 MAGEA10 一抗
  • 描述
    兔多克隆抗体to MAGEA10 - Carboxyterminal end
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the C-terminal region of human MAGEA10.

  • 阳性对照
    • human breast carcinoma tissue and HL60 lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab71788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
IHC-P
  • 应用说明ELISA: 1/1000.
    IHC-P: 1/50 - 1/100.
    WB: 1/100 - 1/500. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa). A range of other bands are detected from ~60-140 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGEA10 contains one MAGE domain. Its function is not known, though it may play a role in embryonal development and tumor transformation or aspects of tumor progression. MAGEA10 is expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
    • 数据库链接
    • 别名
      • Cancer/testis antigen 1.10 antibody
      • cancer/testis antigen family 1, member 10 antibody
      • CT1.10 antibody
      • MAGE 10 antigen antibody
      • MAGE10 antibody
      • Melanoma antigen family A 10 antibody
      • Melanoma associated antigen 10 antibody
      see all

    Anti-MAGEA10 antibody - Carboxyterminal end 图像

    • Anti-MAGEA10 antibody - Carboxyterminal end (ab71788) at 1/100 dilution + HL60 lysate at 12.5 µg

      Predicted band size : 41 kDa
      Observed band size : 41 kDa
    • Formalin-fixed, paraffin-embedded human breast carcinoma tissue reacted with ab71788 at a 1:50 dilution, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

    Anti-MAGEA10 antibody - Carboxyterminal end (ab71788)参考文献

    ab71788 has not yet been referenced specifically in any publications.

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