- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration information loading...
- 纯度Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 31 kDa.
||Use a concentration of 10 µg/ml.
- 功能May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
- 序列相似性Belongs to the MAD2L1BP family.
- 发展阶段During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
- 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
- 细胞定位Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Information by UniProt
- Caught by MAD2 protein antibody
- CMT2 antibody
- dJ261G23.1 antibody
Anti-MAD2L1 binding protein antibody 图像
Anti-MAD2L1 binding protein antibody (ab88611)参考文献
has not yet been referenced specifically in any publications.
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