Anti-MAD2L1 binding protein抗体(ab37584)

概述

  • 产品名称
    Anti-MAD2L1 binding protein抗体
    参阅全部 MAD2L1 binding protein 一抗
  • 描述
    鸡多克隆抗体to MAD2L1 binding protein
  • 经测试应用
    适用于: WBmore details
  • 种属反应性

    预测可用于: Human
  • 免疫原

    Synthetic peptide, corresponding to N terminal amino acids 1-126 of MAD2L1 binding protein

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgY
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab37584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明
    WB: 1/2000. Predicted molecular weight: 31 kDa. We recommend using about 2.5 ug of total protein per lane in the colorimetric detection method, and about 0.25µg for ECL detection.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
    • 序列相似性
      Belongs to the MAD2L1BP family.
    • 发展阶段
      During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
    • 翻译后修饰
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位
      Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Caught by MAD2 protein antibody
      • CMT2 antibody
      • dJ261G23.1 antibody
      • KIAA0110 antibody
      • MAD2L1 binding protein antibody
      • MAD2L1 binding protein isoform 2 antibody
      • MAD2L1-binding protein antibody
      • Mad2l1bp antibody
      • MD2BP_HUMAN antibody
      • MGC11282 antibody
      • OTTHUMP00000016496 antibody
      • RP1 261G23.6 antibody
      see all

    图片

    • Anti-MAD2L1 binding protein antibody (ab37584) at 1/2000 dilution + E coli-derived fusion protein at 2.5 µg

      Secondary
      Goat anti-IgY-HRP at 1/1000 dilution

      Predicted band size : 31 kDa
      Observed band size : 80 kDa (why is the actual band size different from the predicted?)

    实验方案

    文献

    ab37584 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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