- 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
- 存储溶液Preservative: None
Concentration information loading...
- 纯度Immunogen affinity purified
应用说明WB: 1/2000. Predicted molecular weight: 31 kDa. We recommend using about 2.5 ug of total protein per lane in the colorimetric detection method, and about 0.25µg for ECL detection.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- 功能May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
- 序列相似性Belongs to the MAD2L1BP family.
- 发展阶段During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
- 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
- 细胞定位Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Information by UniProt
- Caught by MAD2 protein antibody
- CMT2 antibody
- dJ261G23.1 antibody
Anti-MAD2L1 binding protein antibody 图像
Western blot - MAD2L1 binding protein antibody (ab37584)
Anti-MAD2L1 binding protein antibody (ab37584)参考文献
has not yet been referenced specifically in any publications.
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