Anti-MAD2L1 binding protein抗体(ab102052)

概述

  • 产品名称Anti-MAD2L1 binding protein抗体
    参阅全部 MAD2L1 binding protein 一抗
  • 描述
    兔多克隆抗体to MAD2L1 binding protein
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-306 of Human MAD2L1 binding protein (NP_001003690.1).

  • 阳性对照
    • Mouse liver tissue lysate. Transfected 293T cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab102052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.

靶标

  • 功能May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
  • 序列相似性Belongs to the MAD2L1BP family.
  • 发展阶段During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Caught by MAD2 protein antibody
    • CMT2 antibody
    • dJ261G23.1 antibody
    • KIAA0110 antibody
    • MAD2L1 binding protein antibody
    • MAD2L1 binding protein isoform 2 antibody
    • MAD2L1-binding protein antibody
    • Mad2l1bp antibody
    • MD2BP_HUMAN antibody
    • MGC11282 antibody
    • OTTHUMP00000016496 antibody
    • RP1 261G23.6 antibody
    see all

Anti-MAD2L1 binding protein antibody 图像

  • Anti-MAD2L1 binding protein antibody (ab102052) at 1/500 dilution + Mouse liver lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 31 kDa
  • All lanes : Anti-MAD2L1 binding protein antibody (ab102052) at 1/500 dilution

    Lane 1 : MAD2L1 transfected lysate
    Lane 2 : Non transfected lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 31 kDa

Anti-MAD2L1 binding protein antibody (ab102052)参考文献

ab102052 has not yet been referenced specifically in any publications.

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