Anti-Macrophage Inflammatory Protein 3 beta抗体(ab9831)

概述

  • 产品名称Anti-Macrophage Inflammatory Protein 3 beta抗体
    参阅全部 Macrophage Inflammatory Protein 3 beta 一抗
  • 描述
    兔多克隆抗体to Macrophage Inflammatory Protein 3 beta
  • 经测试应用适用于: WB, ELISA, Neutralisingmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant hMIP-3-b (human macrophage inflammatory protein-3 beta)

性能

应用

Our Abpromise guarantee covers the use of ab9831 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. To detect hMIP-3-b by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hMIP-3-b is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
ELISA Use at an assay dependent concentration. To detect hMIP-3-b by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hMIP-3-b.
Neutralising Use at an assay dependent concentration. To yield one-half maximal inhibition [ND50] of the biological activity of hMIP-3-b (100 ng/ml), a concentration of 2.7 - 4.0 µg/ml of this antibody is required.

靶标

  • 功能May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
  • 组织特异性Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
  • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta chemokine exodus 3 antibody
    • Beta-chemokine exodus-3 antibody
    • C C chemokine ligand 19 antibody
    • C-C motif chemokine 19 antibody
    • CC chemokine ligand 19 antibody
    • CCL 19 antibody
    • CCL19 antibody
    • CCL19_HUMAN antibody
    • Chemokine (C C motif) ligand 19 antibody
    • Chemokine (CC motif) ligand 19 antibody
    • Chemokine C C Motif Ligand 19 antibody
    • Chemokine CC Motif Ligand 19 antibody
    • CK beta 11 antibody
    • CK beta-11 antibody
    • CKb 11 antibody
    • CKb11 antibody
    • EBI 1 ligand chemokine antibody
    • EBI1 ligand chemokine antibody
    • ELC antibody
    • Epstein-Barr virus-induced molecule 1 ligand chemokine antibody
    • Exodus 3 antibody
    • Exodus3 antibody
    • Macrophage inflammatory protein 3 beta antibody
    • MGC34433 antibody
    • MIP 3 beta antibody
    • MIP 3B antibody
    • MIP-3-beta antibody
    • MIP-3b antibody
    • MIP3 beta antibody
    • MIP3B antibody
    • OTTHUMP00000000531 antibody
    • SCYA 19 antibody
    • SCYA19 antibody
    • Small inducible cytokine A19 antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 1 antibody
    • Small-inducible cytokine A19 antibody
    see all

Anti-Macrophage Inflammatory Protein 3 beta antibody (ab9831)参考文献

ab9831 has not yet been referenced specifically in any publications.

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