Anti-Macrophage Inflammatory Protein 3抗体[ANT121] (ab26268)

概述

  • 产品名称Anti-Macrophage Inflammatory Protein 3抗体[ANT121]
    参阅全部 Macrophage Inflammatory Protein 3 一抗
  • 描述
    小鼠单克隆抗体[ANT121] to Macrophage Inflammatory Protein 3
  • 经测试应用适用于: ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human)

性能

应用

Our Abpromise guarantee covers the use of ab26268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 5 µg/ml.

靶标

  • 功能Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
  • 组织特异性High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.
  • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C-C motif chemokine 23 antibody
    • C6 beta chemokine antibody
    • CCL 23 antibody
    • CCL23 antibody
    • CCL23(30-99) antibody
    • CCL23_HUMAN antibody
    • Chemokine CC motif ligand 23 antibody
    • ck beta 8 antibody
    • CK-beta-8 antibody
    • CKB 8 antibody
    • CKB-8 antibody
    • Ckb-8-1 antibody
    • CKB8 antibody
    • Hmrp-2a antibody
    • Macrophage inflammatory protein 3 antibody
    • MIP 3 antibody
    • MIP-3 antibody
    • MIP3 antibody
    • MPIF 1 antibody
    • MPIF-1 antibody
    • MPIF1 antibody
    • Myeloid progenitor inhibitory factor 1 antibody
    • OTTHUMP00000163948 antibody
    • SCYA 23 antibody
    • SCYA23 antibody
    • Small inducible cytokine A 23 antibody
    • Small inducible cytokine subfamily A (Cys-Cys), member 23 antibody
    • Small inducible cytokine subfamily A, member 23 antibody
    • Small-inducible cytokine A23 antibody
    see all

Anti-Macrophage Inflammatory Protein 3 antibody [ANT121] 图像

  • ICC/IF image of ab26268 stained MCF7 cells. The cells were 4% formaldehyde (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab26268, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96879 Dylight 488 goat anti-mouse IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Macrophage Inflammatory Protein 3 antibody [ANT121] (ab26268)参考文献

ab26268 has not yet been referenced specifically in any publications.

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