Anti-Macrophage Inflammatory蛋白3 alpha抗体(ab25123)
Key features and details
- Rabbit polyclonal to Macrophage Inflammatory Protein 3 alpha
- Suitable for: WB
- Isotype: IgG
概述
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产品名称
Anti-Macrophage Inflammatory蛋白3 alpha抗体
参阅全部 Macrophage Inflammatory Protein 3 alpha 一抗 -
描述
兔多克隆抗体to Macrophage Inflammatory蛋白3 alpha -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
免疫原
E.coli expressed recombinant fragment: MACKHLPFLA LAGVLLAYL CSQSEAASN FDCCLTYTK NVYHHARNF VGFTTQMAD EACDINAII, corresponding to N terminal amino acids 1-70 of Rat Macrophage Inflammatory Protein 3 alpha
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 99.9% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25123于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/2000. Predicted molecular weight: 11 kDa.
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说明 |
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WB
1/2000. Predicted molecular weight: 11 kDa. |
靶标
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功能
Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. -
组织特异性
Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon. -
序列相似性
Belongs to the intercrine beta (chemokine CC) family. -
翻译后修饰
C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. -
细胞定位
Secreted. - Information by UniProt
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别名
- Beta chemokine exodus 1 antibody
- Beta-chemokine exodus-1 antibody
- C C motif chemokine ligand 20 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab25123 被引用在 2 文献中.
- Krebs R et al. Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis. Am J Pathol 181:1607-20 (2012). PubMed: 22959907
- Qi W et al. High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism. Nephrol Dial Transplant 22:3147-53 (2007). PubMed: 17664181