Anti-Macrophage Inflammatory Protein 1 alpha / CCL3抗体(ab9673)

概述

  • 产品名称Anti-Macrophage Inflammatory Protein 1 alpha / CCL3抗体
    参阅全部 Macrophage Inflammatory Protein 1 alpha / CCL3 一抗
  • 描述
    山羊多克隆抗体to Macrophage Inflammatory Protein 1 alpha / CCL3
  • 经测试应用适用于: WB, ELISA, Neutralising, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant hMIP-1-alpha (Human macrophage inflammatory protein-1 alpha)

性能

应用

Our Abpromise guarantee covers the use of ab9673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. To detect hMIP-1-alpha by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hMIP-1-alpha is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
ELISA Use at an assay dependent dilution. To detect hMIP-1-alpha by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hMIP-1-alpha.
Neutralising Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution. Can be used as Detection antibody.

靶标

  • 功能Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
  • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
  • 翻译后修饰N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C C motif chemokine 3 antibody
    • CCL 3 antibody
    • CCL3 antibody
    • CCL3_HUMAN antibody
    • Chemokine C C motif ligand 3 antibody
    • G0/G1 switch regulatory protein 19 1 antibody
    • G0/G1 switch regulatory protein 19-1 antibody
    • G0S19 1 antibody
    • G0S19 1 protein antibody
    • Heparin binding chemotaxis protein antibody
    • L2G25B antibody
    • LD78 alpha antibody
    • LD78-alpha(4-69) antibody
    • LD78alpha antibody
    • Macrophage inflammatory protein 1 alpha antibody
    • Macrophage inflammatory protein 1-alpha antibody
    • MIP 1 alpha antibody
    • MIP 1A antibody
    • MIP-1-alpha antibody
    • MIP-1-alpha(4-69) antibody
    • MIP1A antibody
    • PAT 464.1 antibody
    • SCYA 3 antibody
    • SCYA3 antibody
    • SIS alpha antibody
    • SIS beta antibody
    • SIS-beta antibody
    • Small inducible cytokine A3 antibody
    • small inducible cytokine A3 (homologous to mouse Mip-1a) antibody
    • Small-inducible cytokine A3 antibody
    • Tonsillar lymphocyte LD78 alpha protein antibody
    see all

Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (ab9673)参考文献

ab9673 has not yet been referenced specifically in any publications.

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