Anti-MACF1抗体(ab117418)

概述

  • 产品名称Anti-MACF1抗体
  • 描述
    兔多克隆抗体to MACF1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Synthetic peptide, corresponding to N terminal amino acids 1-50 of Mouse MACF1.

  • 阳性对照
    • Mouse kidney tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: Proprietary component, Whole serum
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab117418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Predicted molecular weight: 832 kDa.
ELISA 1/10000.

靶标

  • 相关性Microtubule-actin crosslinking factor 1 (MACF1/ACF7) belongs to spectraplakin family of proteins which also includes mammalian Bpag1/dystonin, Drosophila Short Stop (Shot) and Caenorhabditis elegans Vab-10. These are large actin-microtubule linker molecules that are essential for various biological processes such as neuronal degeneration, wound healing, gastrulation. MACF1, located on mouse chromosome 4D2.2, was found to play an important role during neurogenesis- it was shown that MACF1 regulates the organization of neuronal microtubules which is essential for axon extension. Furthermore, MACF1 is required in controlling focal adhesion assembly and dynamics. MACF1 behaves as an actin-regulated ATPase and it has the ability to target microtubules that track along F-actin to focal adhesions. MACF1 was also implicated in regulating filopodia formation.
  • 细胞定位Cytoplasmic, microtubule. Plasma membrane. Golgi apparatus.
  • 数据库链接
  • 别名
    • ABP620 antibody
    • Acf7 antibody
    • Aclp7 antibody
    • Actin cross linking family 7 antibody
    • MACF antibody
    • Microtubule actin crosslinking factor 1 antibody
    • mKIAA0465 antibody
    • R74989 antibody
    • rabeculin alpha antibody
    see all

Anti-MACF1 antibody 图像

  • ab117418 at 1/500 dilution staining MACF1 in Mouse kidney tissue by Immunofluorescence.

Anti-MACF1 antibody (ab117418)参考文献

ab117418 has not yet been referenced specifically in any publications.

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The first thing I recommend checking is whether the transfer worked. You can do this with a Ponceau Red stain, before you incubate with the antibody. The protei...

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