概述

  • 产品名称Anti-LZTS2抗体
    参阅全部 LZTS2 一抗
  • 描述
    兔多克隆抗体to LZTS2
  • 特异性This antibody is predicted to not cross-react with other LZTS family members.
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to 19 amino acids near the N-terminus of Human LZTS2 (NP_115805).

  • 阳性对照
    • Human kidney tissue lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab124191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 73 kDa.
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
  • 组织特异性Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon.
  • 序列相似性Belongs to the LZTS2 family.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hLZTS2 antibody
    • KIAA1813 antibody
    • LAPSER1 antibody
    • Leucine zipper putative tumor suppressor 2 antibody
    • LZTS2 antibody
    • LZTS2_HUMAN antibody
    • OTTHUMP00000020289 antibody
    • Protein LAPSER1 antibody
    • RP11-108L7.8 antibody
    see all

Anti-LZTS2 antibody 图像

  • Immunofluorescence of LZTS2 in Human kidney tissue with ab124191 at 20 ug/mL.
  • Immunohistochemistry of LZTS2 in Human kidney tissue with ab124191 at 2.5 μg/mL.

  • Anti-LZTS2 antibody (ab124191) at 1 µg/ml + Human kidney tissue lysate at 15 µg

    Predicted band size : 73 kDa

Anti-LZTS2 antibody (ab124191)参考文献

ab124191 has not yet been referenced specifically in any publications.

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