Anti-LYVE1抗体(ab104620)

概述

  • 产品名称Anti-LYVE1抗体
    参阅全部 LYVE1 一抗
  • 描述
    兔多克隆抗体to LYVE1
  • 特异性Detects endogenous level of total lymphatic vessel endothelial hyaluronic acid receptor 1 protein.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide designed around aa 271-275 of Human LYVE1 (conjugated to KLH).

  • 阳性对照
    • MCF cell extracts

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% PBS, 50% Glycerol, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Affinity chromatography with epitope-specific peptide
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab104620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 40 kDa. Abcam recommends incubating membrane overnight at 4oC in 5% non fat milk, 0.1% Tween-20 , with gentle shaking.

靶标

  • 功能Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • 组织特异性Mainly expressed in endothelial cells lining lymphatic vessels.
  • 序列相似性Contains 1 Link domain.
  • 翻译后修饰O-glycosylated.
  • 细胞定位Membrane. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cell surface retention sequence-binding protein 1 antibody
    • CRSBP 1 antibody
    • CRSBP-1 antibody
    • CRSBP1 antibody
    • extracellular link domain containing 1 antibody
    • extracellular link domain-containing 1 antibody
    • Extracellular link domain-containing protein 1 antibody
    • HAR antibody
    • Hyaluronic acid receptor antibody
    • Lymphatic endothelium specific hyaluronan receptor antibody
    • lymphatic vessel endothelial hyaluronan receptor 1 antibody
    • Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody
    • LYVE 1 antibody
    • LYVE-1 antibody
    • LYVE1 antibody
    • LYVE1_HUMAN antibody
    • XLKD1 antibody
    see all

Anti-LYVE1 antibody 图像

Anti-LYVE1 antibody (ab104620)参考文献

ab104620 has not yet been referenced specifically in any publications.

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Thank you for sending your data. I am sorry to see that the antibody is giving the same result as the previous vial. Can you please confirm that these samples are prepared from rat cells? I am going to suggest some alternatives, as we no longer have th...

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I am sorry this product did not perform as stated on the datasheet and for the inconvenience this...

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