Anti-LYVE1抗体(ab104620)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to LYVE1
  • 特异性
    Detects endogenous level of total lymphatic vessel endothelial hyaluronic acid receptor 1 protein.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide designed around aa 271-275 of Human LYVE1 (conjugated to KLH).

  • 阳性对照
    • MCF cell extracts

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 50% PBS, 50% Glycerol, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Affinity chromatography with epitope-specific peptide
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab104620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 40 kDa. Abcam recommends incubating membrane overnight at 4oC in 5% non fat milk, 0.1% Tween-20 , with gentle shaking.

靶标

  • 功能
    Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • 组织特异性
    Mainly expressed in endothelial cells lining lymphatic vessels.
  • 序列相似性
    Contains 1 Link domain.
  • 翻译后修饰
    O-glycosylated.
  • 细胞定位
    Membrane. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cell surface retention sequence-binding protein 1 antibody
    • CRSBP 1 antibody
    • CRSBP-1 antibody
    • CRSBP1 antibody
    • extracellular link domain containing 1 antibody
    • extracellular link domain-containing 1 antibody
    • Extracellular link domain-containing protein 1 antibody
    • HAR antibody
    • Hyaluronic acid receptor antibody
    • Lymphatic endothelium specific hyaluronan receptor antibody
    • lymphatic vessel endothelial hyaluronan receptor 1 antibody
    • Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody
    • LYVE 1 antibody
    • LYVE-1 antibody
    • LYVE1 antibody
    • LYVE1_HUMAN antibody
    • XLKD1 antibody
    see all

图片

实验方案

文献

ab104620 has not yet been referenced specifically in any publications.

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Thank you for the extra details about your samples.

The mouse western blot data on the ab33682 datasheet looks encouraging, and the immunogen for ab33682 is completely conserved in the amino acid sequence given at the following entry (unrevi...

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Thank you for sending your data. I am sorry to see that the antibody is giving the same result as the previous vial. Can you please confirm that these samples are prepared from rat cells? I am going to suggest some alternatives, as we no longer have th...

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I am sorry this product did not perform as stated on the datasheet and for the inconvenience this...

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