概述

  • 产品名称
    Anti-LYVE1抗体[4G1]
    参阅全部 LYVE1 一抗
  • 描述
    小鼠单克隆抗体[4G1] to LYVE1
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human LYVE-1 (25-235 aa) purified from E. coli.

  • 阳性对照
    • A549 cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 克隆编号
    4G1
  • 骨髓瘤
    Sp2/0
  • 同种型
    IgG2b
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab33477 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB 1/500 - 1/1000. Detects a band of approximately 38 kDa (predicted molecular weight: 35 kDa).

靶标

  • 功能
    Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • 组织特异性
    Mainly expressed in endothelial cells lining lymphatic vessels.
  • 序列相似性
    Contains 1 Link domain.
  • 翻译后修饰
    O-glycosylated.
  • 细胞定位
    Membrane. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cell surface retention sequence-binding protein 1 antibody
    • CRSBP 1 antibody
    • CRSBP-1 antibody
    • CRSBP1 antibody
    • extracellular link domain containing 1 antibody
    • extracellular link domain-containing 1 antibody
    • Extracellular link domain-containing protein 1 antibody
    • HAR antibody
    • Hyaluronic acid receptor antibody
    • Lymphatic endothelium specific hyaluronan receptor antibody
    • lymphatic vessel endothelial hyaluronan receptor 1 antibody
    • Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody
    • LYVE 1 antibody
    • LYVE-1 antibody
    • LYVE1 antibody
    • LYVE1_HUMAN antibody
    • XLKD1 antibody
    see all

Anti-LYVE1 antibody [4G1] 图像

  • Anti-LYVE1 antibody [4G1] (ab33477) at 1/500 dilution + A549 (lung carcinoma) cell lysate

    Secondary
    goat anti-mouse secondary antibody conjugated to HRP
    Developed using the ECL technique

    Predicted band size : 35 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • ICC/IF analysis of LYVE-1 in A549 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human LYVE-1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

实验方案

Anti-LYVE1 antibody [4G1] (ab33477)参考文献

ab33477 has not yet been referenced specifically in any publications.

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