概述

  • 产品名称Anti-LY75抗体[NLDC-145] (Biotin)
    参阅全部 LY75 一抗
  • 描述
    大鼠单克隆抗体[NLDC-145] to LY75 (Biotin)
  • 偶联物Biotin
  • 特异性Reacts with Mouse non lymphoid dendritic cells: interdigitating cells (IDC), veiled cells and Langerhans cells, thymic epithelial cells.
  • 经测试应用适用于: Flow Cyt, IHC-Frmore details
    不适用于: IHC-P
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse lymph node tissue

  • 表位The antigen is a protein of 205kDa molecular weight which is localized on the cell surface and intracellularly. The epitope has not been further characterized.
  • 阳性对照
    • The following tissues also tested positive: Lymph node, Peyer’s patch, Thymus and Skin.

性能

应用

Our Abpromise guarantee covers the use of ab51820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
IHC-Fr
  • 应用说明Flow Cyt: Use at an assay dependent dilution (PMID 19109143).
    IHC-Fr: Use at a concentration of 3 µg/ml.


    Is unsuitable for IHC-P.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
    • 组织特异性Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
    • 序列相似性Contains 10 C-type lectin domains.
      Contains 1 fibronectin type-II domain.
      Contains 1 ricin B-type lectin domain.
    • 翻译后修饰N-glycosylated.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C-type lectin domain family 13 member B antibody
      • CD 205 antibody
      • CD205 antibody
      • CD205 antigen antibody
      • CLEC 13B antibody
      • CLEC13B antibody
      • DEC 205 antibody
      • DEC-205 antibody
      • DEC205 antibody
      • gp200 antibody
      • gp200 MR6 antibody
      • gp200-MR6 antibody
      • LY 75 antibody
      • Ly-75 antibody
      • LY75 antibody
      • LY75_HUMAN antibody
      • Lymphocyte antigen 75 antibody
      • Renal Cell Carcinoma (gp200) antibody
      see all

    Anti-LY75 antibody [NLDC-145] (Biotin) (ab51820)参考文献

    This product has been referenced in:
    • Jenkinson SR  et al. TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development. Proc Natl Acad Sci U S A 110:21107-12 (2013). Mouse . Read more (PubMed: 24324158) »
    • Sitnik KM  et al. Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis. J Immunol 188:4801-9 (2012). Flow Cyt ; Mouse . Read more (PubMed: 22504647) »

    See all 6 Publications for this product

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