概述

  • 产品名称Anti-Ly6c抗体[HK1.4]
    参阅全部 Ly6c 一抗
  • 描述
    大鼠单克隆抗体[HK1.4] to Ly6c
  • 经测试应用适用于: Celluar Activation, Flow Cyt, IHC-Frmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    L3 cloned CTL cells

性能

应用

Our Abpromise guarantee covers the use of ab24973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Celluar Activation
Flow Cyt
IHC-Fr
  • 应用说明Cellular activation: Use at an assay dependent dilution.
    Flow Cyt: Use 1µg for 106 cells.
    IHC-Fr: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Mice with the Ly6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly6C+ and CD8+Ly6C+ cells, while Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly6C+ lymphocytes.
    • 细胞定位Cell membrane; Lipid-anchor, GPI-anchor.
    • 数据库链接
    • 别名
      • Ly 6c antibody
      • Ly6c protein antibody
      • Ly6c1 antibody
      • Ly6c2 antibody
      • Lymphocyte antigen 6 complex antibody
      • Lymphocyte antigen 6 complex locus C antibody
      • Lymphocyte antigen 6C antibody
      • Lymphocyte antigen 6C1 antibody
      • Lymphocyte antigen 6C2 antibody
      • Lymphocyte antigen Ly 6C antibody
      see all

    Anti-Ly6c antibody [HK1.4] 图像

    • Bone marrow cells from C57BL/6 mice were labeled with ab24973 and then stained with goat anti-rat IgG-FITC. Large cells were gated and analyzed by flow cytometry.

    Anti-Ly6c antibody [HK1.4] (ab24973)参考文献

    This product has been referenced in:
    • Zhao C  et al. Nuclear Factor E2-related Factor-2 (Nrf2) Is Required for NLRP3 and AIM2 Inflammasome Activation. J Biol Chem 289:17020-17029 (2014). Flow Cyt . Read more (PubMed: 24798340) »
    • Makaroff LE  et al. Postthymic maturation influences the CD8 T cell response to antigen. Proc Natl Acad Sci U S A 106:4799-804 (2009). Flow Cyt ; Mouse . Read more (PubMed: 19270077) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab24973.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"