LY 341495 disodium salt (ab120818)

概述

  • 产品名称
    LY 341495 disodium salt
  • 描述
    Water-soluble group II/group III mGlu antagonist. Disodium salt of LY 341495 (ab120199).
  • 生物学描述
    Water-soluble and very selective nanomolar potent antagonist for group II mGlu receptors. Also a relatively potent antagonist for group III mGlu receptors at high nanomolar to low micromolar concentrations. Disodium salt of LY 341495 (ab120199) which displays Kd values of 1.67 (human mGlu2), 0.75 (mGlu3), 31.6 (mGlu6), 72.7 (mGlu7a) and 14 (human mGlu8a receptors) nM. LY 341495 displays IC50 values of 7.8, 8.2 and 22 μM for mGlu1a, mGlu5a and mGlu4 receptors, respectively. It is readily brain penetrant and active in vivo.

    Also available in simple stock solutions (ab144500) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 纯度
    > 98%

性能

文献

ab120818 has not yet been referenced specifically in any publications.

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