Anti-LXR beta抗体(ab24361)

概述

  • 产品名称Anti-LXR beta抗体
    参阅全部 LXR beta 一抗
  • 描述
    山羊多克隆抗体to LXR beta
  • 特异性Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide:

    SSPTTSSLDT PLPG(C)

    , corresponding to N terminal amino acids 2-14 of Human LXR beta

  • 阳性对照
    • Lysate prepared from human bone marrow. Human spleen tissue.

性能

应用

Our Abpromise guarantee covers the use of ab24361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 60, 80 kDa (predicted molecular weight: 51 kDa).
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Liver X nuclear receptor beta antibody
    • Liver X receptor beta antibody
    • LX receptor beta antibody
    • LXR b antibody
    • LXR beta antibody
    • LXRB antibody
    • NER antibody
    • NER I antibody
    • NER1 antibody
    • NR1H 2 antibody
    • NR1H2 antibody
    • NR1H2_HUMAN antibody
    • Nuclear orphan receptor LXR beta antibody
    • Nuclear receptor NER antibody
    • Nuclear receptor subfamily 1 group H member 2 antibody
    • OR-1 antibody
    • Oxysterols receptor LXR-beta antibody
    • RIP15 antibody
    • Steroid hormone nuclear receptor NER antibody
    • Ubiquitously-expressed nuclear receptor antibody
    • UNR antibody
    see all

Anti-LXR beta antibody 图像

  • Anti-LXR beta antibody (ab24361) at 1 µg/ml + Human Bone Marrow lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 51 kDa
    Observed band size : 60,80 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour
  • ab24361 at 3µg/ml staining LXR beta in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections). Tissue underwent antigen retrieval in steam in citrate buffer pH 6.0. AP staining procedure was used for detection.

Anti-LXR beta antibody (ab24361)参考文献

ab24361 has not yet been referenced specifically in any publications.

Product Wall

Merci de nous avoir contactés.

Garantie sur les produits Abcam: nos produitssont garantis pour fonctionner tels qu'ils sont décrits sur la fiche technique (garantie Abpromise). Nous pouvons donc toujours résoudre un probl...

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Thank you foryour message.

I can confirm that you will need to dilute the antibody before you use it in an experiment.

We recommend to only dilute the amount of antibody you need. The rest should be stored undiluted as recommended...

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Thank you for your message

As stated on the datasheet, the vial size is 100 µg. This is the only size we provide for this product.

As my customer service colleague has previously discussed with you, unfortunately, Abcam does...

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Thank you for your enquiry and your interest in our products.

We have several antibodies against LXR beta (ab24361, ab56237, ab58089, ab58092, ab76983, ab106473) . The tested application/species/unit size can be found on the on-line product d...

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Thank you for your email. For both of these antibodies, ab3585 and ab24361, they have only so been tested for cross-reactivity with human and have not yet been tested in other species. Ab24361 is predicted to react with Mouse (85% identity with immunog...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"