Mouse, Rat, Human
Recombinant fragment, corresponding to amino acids 1-222 of Human LXN.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500. Predicted molecular weight: 25 kDa.
Use at an assay dependent concentration.
Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4.
Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.
Belongs to the protease inhibitor I47 (latexin) family.
Information by UniProt
Endogenous carboxypeptidase inhibitor antibody
Anti-LXN antibody (ab14057)参考文献
This product has been referenced in:
et al. Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway. Cell Death Dis 5:e1493 (2014).
Read more (PubMed: 25341047) »
et al. Latexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth. PLoS One 7:e44979 (2012).
Read more (PubMed: 23028717) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"