概述

  • 产品名称
    Anti-LRRC8C抗体
  • 描述
    兔多克隆抗体to LRRC8C
  • 经测试应用
    适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen, corresponding to amino acids 662-792 of Human LRRC8C (Q8TDW0).

  • 阳性对照
    • Human colon tissue

性能

应用

Our Abpromise guarantee covers the use of ab122046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    May play a role in adipogenesis.
  • 组织特异性
    Expressed at highest levels in skeletal muscle, and at moderate levels in heart, lung and peripheral blood leukocytes.
  • 序列相似性
    Contains 17 LRR (leucine-rich) repeats.
  • 细胞定位
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AD158 antibody
    • AI326115 antibody
    • E430036I04Rik antibody
    • Factor for adipocyte differentiation 158 antibody
    • FAD158 antibody
    • Leucine-rich repeat-containing protein 8C antibody
    • LRC8C_HUMAN antibody
    • LRRC8C antibody
    see all

图片

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in golgi apparatus. Recommended concentration of ab122046 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122046, at 1/20, staining LRRC8C in paraffin embedded Human colon tissue by Immunohistochemistry.

文献

ab122046 has not yet been referenced specifically in any publications.

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