概述

  • 产品名称Anti-LRRC26抗体
    参阅全部 LRRC26 一抗
  • 描述
    兔多克隆抗体to LRRC26
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 288-319 of Human LRRC26 (NP_001013675.1).

  • 阳性对照
    • A549 cell line lysate
  • 常规说明Store in small aliquots and prevent freeze-thaw cycles

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明This antibody is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab124181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.

靶标

  • 功能Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium.
  • 组织特异性Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines.
  • 序列相似性Contains 5 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • 结构域The transmembrane domain is necessary for interaction with KCNMA1.
  • 细胞定位Membrane. Cytoplasm > cytoskeleton. Although predicted to be a single-pass type I membrane protein, this protein localizes to the cytoplasm when expressed at high levels.
  • Information by UniProt
  • 数据库链接
  • 形式There are 2 isoforms produced by alternative splicing. Isoform 1 = L-CAPC. Isoform 2 = S-CAPC and does not contain the immunogen sequence.
  • 别名
    • bA350O14.10 antibody
    • CAPC antibody
    • cytokeratin-associated protein antibody
    • Cytokeratin-associated protein in cancer antibody
    • Leucine-rich repeat-containing protein 26 antibody
    • LRC26_HUMAN antibody
    • Lrrc26 antibody
    see all

Anti-LRRC26 antibody 图像

  • Anti-LRRC26 antibody (ab124181) at 1/100 dilution + A549 cell line lysate at 35 µg

    Predicted band size : 34 kDa

Anti-LRRC26 antibody (ab124181)参考文献

ab124181 has not yet been referenced specifically in any publications.

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