概述

  • 产品名称LRP5 + LRP6肽

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab51923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 纯度> 90 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • BMND1
    • EVR 4
    • EVR1
    • EVR4
    • HBM
    • Low density lipoprotein receptor related protein 5
    • Low density lipoprotein receptor related protein 6
    • LR3
    • LRP7
    • OPPG
    • OPS
    • OPTA1
    • VBCH2
    see all
  • 相关性LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.
  • 细胞定位Membrane; single-pass type I membrane protein

LRP5 + LRP6 peptide (ab51923)参考文献

ab51923 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"