概述

  • 产品名称Anti-LRP3抗体
    参阅全部 LRP3 一抗
  • 描述
    兔多克隆抗体to LRP3
  • 特异性ab74100 detects endogenous levels of total LRP3 protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthesized peptide derived from an internal sequence of human LRP3.

  • 阳性对照
    • Extracts from RAW264.7 cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab74100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 83 kDa.
ELISA 1/40000.

靶标

  • 功能Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
  • 组织特异性Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
  • 序列相似性Belongs to the LDLR family.
    Contains 2 CUB domains.
    Contains 4 LDL-receptor class A domains.
  • 细胞定位Membrane. Membrane > coated pit.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 105 kDa low-density lipoprotein receptor-related protein antibody
    • CTD-2540B15.13 antibody
    • hLRp105 antibody
    • Low density lipoprotein receptor related protein 3 antibody
    • Low-density lipoprotein receptor-related protein 3 antibody
    • LRP-3 antibody
    • Lrp3 antibody
    • LRP3_HUMAN antibody
    see all

Anti-LRP3 antibody 图像

  • All lanes : Anti-LRP3 antibody (ab74100) at 1/500 dilution

    Lane 1 : Extracts from RAW264.7 cells with no peptide
    Lane 2 : Extracts from RAW264.7 cells with immunizing peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 83 kDa
    Observed band size : 83 kDa

Anti-LRP3 antibody (ab74100)参考文献

ab74100 has not yet been referenced specifically in any publications.

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